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Gene expression analysis of Drosophilaa Manf mutants reveals perturbations in membrane traffic and major metabolic changes

BACKGROUND: MANF and CDNF are evolutionarily conserved neurotrophic factors that specifically support dopaminergic neurons. To date, the receptors and signalling pathways of this novel MANF/CDNF family have remained unknown. Independent studies have showed upregulation of MANF by unfolded protein re...

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Detalles Bibliográficos
Autores principales: Palgi, Mari, Greco, Dario, Lindström, Riitta, Auvinen, Petri, Heino, Tapio I
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364883/
https://www.ncbi.nlm.nih.gov/pubmed/22494833
http://dx.doi.org/10.1186/1471-2164-13-134