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The leukemia associated nuclear corepressor ETO homologue genes MTG16 and MTGR1 are regulated differently in hematopoietic cells

BACKGROUND: MTG16, MTGR1 and ETO are nuclear transcriptional corepressors of the human ETO protein family. MTG16 is implicated in hematopoietic development and in controlling erythropoiesis/megakaryopoiesis. Furthermore, ETO homologue genes are 3'participants in leukemia fusions generated by ch...

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Detalles Bibliográficos
Autores principales: Ajore, Ram, Kumar, Parveen, Dhanda, Rakesh Singh, Gullberg, Urban, Olsson, Inge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364894/
https://www.ncbi.nlm.nih.gov/pubmed/22443175
http://dx.doi.org/10.1186/1471-2199-13-11