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Loss of nonsense mediated decay suppresses mutations in Saccharomyces cerevisiae TRA1

BACKGROUND: Tra1 is an essential protein in Saccharomyces cerevisiae. It was first identified in the SAGA and NuA4 complexes, both with functions in multiple aspects of gene regulation and DNA repair, and recently found in the ASTRA complex. Tra1 belongs to the PIKK family of proteins with a C-termi...

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Detalles Bibliográficos
Autores principales: Kvas, Stephanie, Gloor, Gregory B, Brandl, Christopher J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364908/
https://www.ncbi.nlm.nih.gov/pubmed/22439631
http://dx.doi.org/10.1186/1471-2156-13-19