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Quality of Computationally Inferred Gene Ontology Annotations

Gene Ontology (GO) has established itself as the undisputed standard for protein function annotation. Most annotations are inferred electronically, i.e. without individual curator supervision, but they are widely considered unreliable. At the same time, we crucially depend on those automated annotat...

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Detalles Bibliográficos
Autores principales: Škunca, Nives, Altenhoff, Adrian, Dessimoz, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364937/
https://www.ncbi.nlm.nih.gov/pubmed/22693439
http://dx.doi.org/10.1371/journal.pcbi.1002533