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Structure and Age Jointly Influence Rates of Protein Evolution

What factors determine a protein's rate of evolution are actively debated. Especially unclear is the relative role of intrinsic factors of present-day proteins versus historical factors such as protein age. Here we study the interplay of structural properties and evolutionary age, as determinan...

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Detalles Bibliográficos
Autores principales: Toll-Riera, Macarena, Bostick, David, Albà, M. Mar, Plotkin, Joshua B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364943/
https://www.ncbi.nlm.nih.gov/pubmed/22693443
http://dx.doi.org/10.1371/journal.pcbi.1002542