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Effect of Levels of Acetate on the Mevalonate Pathway of Borrelia burgdorferi

Borrelia burgdorferi, the agent of Lyme disease, is a spirochetal pathogen with limited metabolic capabilities that survives under highly disparate host-specific conditions. However, the borrelial genome encodes several proteins of the mevalonate pathway (MP) that utilizes acetyl-CoA as a substrate...

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Detalles Bibliográficos
Autores principales: Van Laar, Tricia A., Lin, Ying-Han, Miller, Christine L., Karna, S. L. Rajasekhar, Chambers, James P., Seshu, J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364977/
https://www.ncbi.nlm.nih.gov/pubmed/22675445
http://dx.doi.org/10.1371/journal.pone.0038171