Inhibition of Specific NF-κB Activity Contributes to the Tumor Suppressor Function of 14-3-3σ in Breast Cancer

14-3-3σ is frequently lost in human breast cancers by genetic deletion or promoter methylation. We have now investigated the involvement of 14-3-3σ in the termination of NF-κB signal in mammary cells and its putative role in cancer relapse and metastasis. Our results show that 14-3-3σ regulates nucl...

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Detalles Bibliográficos
Autores principales: Inglés-Esteve, Julia, Morales, Mònica, Dalmases, Alba, Garcia-Carbonell, Ricard, Jené-Sanz, Alba, López-Bigas, Núria, Iglesias, Mar, Ruiz-Herguido, Cristina, Rovira, Ana, Rojo, Federico, Albanell, Joan, Gomis, Roger R., Bigas, Anna, Espinosa, Lluís
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364992/
https://www.ncbi.nlm.nih.gov/pubmed/22675457
http://dx.doi.org/10.1371/journal.pone.0038347

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364992/
https://www.ncbi.nlm.nih.gov/pubmed/22675457
http://dx.doi.org/10.1371/journal.pone.0038347

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