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Transactivation of EGFR by LPS Induces COX-2 Expression in Enterocytes

Necrotizing enterocolitis (NEC) is the leading cause of gastrointestinal morbidity and mortality in preterm infants. NEC is characterized by an exaggerated inflammatory response to bacterial flora leading to bowel necrosis. Bacterial lipopolysaccharide (LPS) mediates inflammation through TLR4 activa...

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Detalles Bibliográficos
Autores principales: McElroy, Steven J., Hobbs, Stuart, Kallen, Michael, Tejera, Noemi, Rosen, Michael J., Grishin, Anatoly, Matta, Poojitha, Schneider, Claus, Upperman, Jeffrey, Ford, Henri, Polk, D. Brent, Weitkamp, Jörn-Hendrik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364993/
https://www.ncbi.nlm.nih.gov/pubmed/22675459
http://dx.doi.org/10.1371/journal.pone.0038373