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Acrolein Induces Endoplasmic Reticulum Stress and Causes Airspace Enlargement

BACKGROUND: Given the relative abundance and toxic potential of acrolein in inhaled cigarette smoke, it is surprising how little is known about the pulmonary and systemic effects of acrolein. Here we test the hypothesis whether systemic administration of acrolein could cause endoplasmic reticulum (E...

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Detalles Bibliográficos
Autores principales: Kitaguchi, Yoshiaki, Taraseviciene-Stewart, Laimute, Hanaoka, Masayuki, Natarajan, Ramesh, Kraskauskas, Donatas, Voelkel, Norbert F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3364999/
https://www.ncbi.nlm.nih.gov/pubmed/22675432
http://dx.doi.org/10.1371/journal.pone.0038038