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Specific Recognition of p53 Tetramers by Peptides Derived from p53 Interacting Proteins
Oligomerization plays a major role in regulating the activity of many proteins, and in modulating their interactions. p53 is a homotetrameric transcription factor that has a pivotal role in tumor suppression. Its tetramerization domain is contained within its C-terminal domain, which is a site for n...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365014/ https://www.ncbi.nlm.nih.gov/pubmed/22693587 http://dx.doi.org/10.1371/journal.pone.0038060 |