Association of Estimated Glomerular Filtration Rate and Urinary Uromodulin Concentrations with Rare Variants Identified by UMOD Gene Region Sequencing

BACKGROUND: Recent genome-wide association studies (GWAS) have identified common variants in the UMOD region associated with kidney function and disease in the general population. To identify novel rare variants as well as common variants that may account for this GWAS signal, the exons and 4 kb ups...

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Detalles Bibliográficos
Autores principales: Köttgen, Anna, Yang, Qiong, Shimmin, Lawrence C., Tin, Adrienne, Schaeffer, Céline, Coresh, Josef, Liu, Xuan, Rampoldi, Luca, Hwang, Shih-Jen, Boerwinkle, Eric, Hixson, James E., Kao, W. H. Linda, Fox, Caroline S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365030/
https://www.ncbi.nlm.nih.gov/pubmed/22693617
http://dx.doi.org/10.1371/journal.pone.0038311

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365030/
https://www.ncbi.nlm.nih.gov/pubmed/22693617
http://dx.doi.org/10.1371/journal.pone.0038311

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