Adaptive Evolution of HIV at HLA Epitopes Is Associated with Ethnicity in Canada

Host immune selection pressure influences the development of mutations that allow for HIV escape. Mutation patterns induced in HIV by the human leukocyte antigen (HLA) are HLA-allele specific. As ethnic groups have distinct and characteristic HLA allele frequencies, we can expect divergent viral evo...

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Detalles Bibliográficos
Autores principales: Ragonnet-Cronin, Manon, Aris-Brosou, Stéphane, Joanisse, Isabelle, Merks, Harriet, Vallee, Dominic, Caminiti, Kyna, Sandstrom, Paul, Brooks, James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365047/
https://www.ncbi.nlm.nih.gov/pubmed/22693560
http://dx.doi.org/10.1371/journal.pone.0036933

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365047/
https://www.ncbi.nlm.nih.gov/pubmed/22693560
http://dx.doi.org/10.1371/journal.pone.0036933

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