A Chaperone Trap Contributes to the Onset of Cystic Fibrosis

Protein folding is the primary role of proteostasis network (PN) where chaperone interactions with client proteins determine the success or failure of the folding reaction in the cell. We now address how the Phe508 deletion in the NBD1 domain of the cystic fibrosis (CF) transmembrane conductance reg...

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Detalles Bibliográficos
Autores principales: Coppinger, Judith A., Hutt, Darren M., Razvi, Abbas, Koulov, Atanas V., Pankow, Sandra, Yates, John R., Balch, William E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365120/
https://www.ncbi.nlm.nih.gov/pubmed/22701530
http://dx.doi.org/10.1371/journal.pone.0037682

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365120/
https://www.ncbi.nlm.nih.gov/pubmed/22701530
http://dx.doi.org/10.1371/journal.pone.0037682

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