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A stereochemical switch in the aDrs model system, a candidate for a functional amyloid

Amyloid fibrils are commonly observed to adopt multiple distinct morphologies, which eventually can have significantly different neurotoxicities, as e.g. demonstrated in case of the Alzheimer peptide. The architecture of amyloid deposits is apparently also determined by the stereochemistry of amino...

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Detalles Bibliográficos
Autores principales: Gößler-Schöfberger, Ruth, Hesser, Günter, Reif, Maria M., Friedmann, Jacqueline, Duscher, Bernadette, Toca-Herrera, José Luis, Oostenbrink, Chris, Jilek, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365241/
https://www.ncbi.nlm.nih.gov/pubmed/22510364
http://dx.doi.org/10.1016/j.abb.2012.04.006