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Role of the transcription factor Bcl11b in development and lymphomagenesis

Bcl11b is a lineage-specific transcription factor expressed in various cell types and its expression is important for development of T cells, neurons and others. On the other hand, Bcl11b is a haploinsufficient tumor suppressor and loss of a Bcl11b allele provides susceptibility to mouse thymic lymp...

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Detalles Bibliográficos
Autor principal: KOMINAMI, Ryo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japan Academy 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365246/
https://www.ncbi.nlm.nih.gov/pubmed/22450536
http://dx.doi.org/10.2183/pjab.88.72