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Genome-wide association study of Alzheimer's disease

In addition to apolipoprotein E (APOE), recent large genome-wide association studies (GWASs) have identified nine other genes/loci (CR1, BIN1, CLU, PICALM, MS4A4/MS4A6E, CD2AP, CD33, EPHA1 and ABCA7) for late-onset Alzheimer's disease (LOAD). However, the genetic effect attributable to known lo...

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Detalles Bibliográficos
Autores principales: Kamboh, M I, Demirci, F Y, Wang, X, Minster, R L, Carrasquillo, M M, Pankratz, V S, Younkin, S G, Saykin, A J, Jun, G, Baldwin, C, Logue, M W, Buros, J, Farrer, L, Pericak-Vance, M A, Haines, J L, Sweet, R A, Ganguli, M, Feingold, E, DeKosky, S T, Lopez, O L, Barmada, M M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365264/
https://www.ncbi.nlm.nih.gov/pubmed/22832961
http://dx.doi.org/10.1038/tp.2012.45