Real-time monitoring in three-dimensional hepatocytes reveals that insulin acts as a synchronizer for liver clock

Resetting the peripheral clock and understanding the integration between the circadian rhythm and metabolic pathways are fundamental questions. To test whether insulin acts as a synchronizer for the hepatic clock by cell-autonomous mechanisms, the phase-resetting capabilities of insulin were investi...

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Detalles Bibliográficos
Autores principales: Yamajuku, Daisuke, Inagaki, Takahiko, Haruma, Tomonori, Okubo, Shingo, Kataoka, Yutaro, Kobayashi, Satoru, Ikegami, Keisuke, Laurent, Thomas, Kojima, Tomoko, Noutomi, Keiji, Hashimoto, Seiichi, Oda, Hiroaki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365280/
https://www.ncbi.nlm.nih.gov/pubmed/22666542
http://dx.doi.org/10.1038/srep00439

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365280/
https://www.ncbi.nlm.nih.gov/pubmed/22666542
http://dx.doi.org/10.1038/srep00439

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