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Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells
Epigenetic treatment concepts have long been ascribed as being tumour-selective. Over the last decade, it has become evident that epigenetic mechanisms are essential for a wide range of intracellular functions in healthy cells as well. Evaluation of possible side-effects and their underlying mechani...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer-Verlag
2010
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365366/ https://www.ncbi.nlm.nih.gov/pubmed/22704088 http://dx.doi.org/10.1007/s13148-010-0007-1 |