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Targeting the epigenome: effects of epigenetic treatment strategies on genomic stability in healthy human cells

Epigenetic treatment concepts have long been ascribed as being tumour-selective. Over the last decade, it has become evident that epigenetic mechanisms are essential for a wide range of intracellular functions in healthy cells as well. Evaluation of possible side-effects and their underlying mechani...

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Detalles Bibliográficos
Autores principales: Purrucker, Jan C., Mahlknecht, Ulrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2010
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365366/
https://www.ncbi.nlm.nih.gov/pubmed/22704088
http://dx.doi.org/10.1007/s13148-010-0007-1