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Epigenetic abnormalities in myeloproliferative neoplasms: a target for novel therapeutic strategies

The myeloproliferative neoplasms (MPNs) are a group of clonal hematological malignancies characterized by a hypercellular bone marrow and a tendency to develop thrombotic complications and to evolve to myelofibrosis and acute leukemia. Unlike chronic myelogenous leukemia, where a single disease-init...

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Detalles Bibliográficos
Autores principales: Mascarenhas, John, Roper, Nitin, Chaurasia, Pratima, Hoffman, Ronald
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2011
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365400/
https://www.ncbi.nlm.nih.gov/pubmed/22704337
http://dx.doi.org/10.1007/s13148-011-0050-6