Interleukin-6 counteracts therapy-induced cellular oxidative stress in multiple myeloma by up-regulating manganese superoxide dismutase

IL (interleukin)-6, an established growth factor for multiple myeloma cells, induces myeloma therapy resistance, but the resistance mechanisms remain unclear. The present study determines the role of IL-6 in re-establishing intracellular redox homoeostasis in the context of myeloma therapy. IL-6 tre...

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Detalles Bibliográficos
Autores principales: Brown, Charles O., Salem, Kelley, Wagner, Brett A., Bera, Soumen, Singh, Neeraj, Tiwari, Ajit, Choudhury, Amit, Buettner, Garry R., Goel, Apollina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Portland Press Ltd. 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365439/
https://www.ncbi.nlm.nih.gov/pubmed/22471522
http://dx.doi.org/10.1042/BJ20112019

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365439/
https://www.ncbi.nlm.nih.gov/pubmed/22471522
http://dx.doi.org/10.1042/BJ20112019

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