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Stoichiometry of Nck-dependent actin polymerization in living cells

Regulation of actin dynamics through the Nck/N-WASp (neural Wiskott–Aldrich syndrome protein)/Arp2/3 pathway is essential for organogenesis, cell invasiveness, and pathogen infection. Although many of the proteins involved in this pathway are known, the detailed mechanism by which it functions remai...

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Detalles Bibliográficos
Autores principales: Ditlev, Jonathon A., Michalski, Paul J., Huber, Greg, Rivera, Gonzalo M., Mohler, William A., Loew, Leslie M., Mayer, Bruce J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365498/
https://www.ncbi.nlm.nih.gov/pubmed/22613834
http://dx.doi.org/10.1083/jcb.201111113