Basement membrane assembly of the integrin α8β1 ligand nephronectin requires Fraser syndrome–associated proteins

Dysfunction of the basement membrane protein QBRICK provokes Fraser syndrome, which results in renal dysmorphogenesis, cryptophthalmos, syndactyly, and dystrophic epidermolysis bullosa through unknown mechanisms. Here, we show that integrin α8β1 binding to basement membranes was significantly impair...

Descripción completa

Detalles Bibliográficos
Autores principales: Kiyozumi, Daiji, Takeichi, Makiko, Nakano, Itsuko, Sato, Yuya, Fukuda, Tomohiko, Sekiguchi, Kiyotoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2012
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365501/
https://www.ncbi.nlm.nih.gov/pubmed/22613833
http://dx.doi.org/10.1083/jcb.201203065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365501/
https://www.ncbi.nlm.nih.gov/pubmed/22613833
http://dx.doi.org/10.1083/jcb.201203065

Ejemplares similares