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Disulfide Bridges Remain Intact while Native Insulin Converts into Amyloid Fibrils
Amyloid fibrils are β-sheet-rich protein aggregates commonly found in the organs and tissues of patients with various amyloid-associated diseases. Understanding the structural organization of amyloid fibrils can be beneficial for the search of drugs to successfully treat diseases associated with pro...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365881/ https://www.ncbi.nlm.nih.gov/pubmed/22675475 http://dx.doi.org/10.1371/journal.pone.0036989 |