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Optimisation of Over-Expression in E. coli and Biophysical Characterisation of Human Membrane Protein Synaptogyrin 1

Progress in functional and structural studies of integral membrane proteins (IMPs) is lacking behind their soluble counterparts due to the great challenge in producing stable and homogeneous IMPs. Low natural abundance, toxicity when over-expressed and potential lipid requirements of IMPs are only a...

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Detalles Bibliográficos
Autores principales: Löw, Christian, Jegerschöld, Caroline, Kovermann, Michael, Moberg, Per, Nordlund, Pär
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365889/
https://www.ncbi.nlm.nih.gov/pubmed/22675529
http://dx.doi.org/10.1371/journal.pone.0038244