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BRCA1 Regulates Follistatin Function in Ovarian Cancer and Human Ovarian Surface Epithelial Cells

Follistatin (FST), a folliculogenesis regulating protein, is found in relatively high concentrations in female ovarian tissues. FST acts as an antagonist to Activin, which is often elevated in human ovarian carcinoma, and thus may serve as a potential target for therapeutic intervention against ovar...

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Detalles Bibliográficos
Autores principales: Karve, Tejaswita M., Preet, Anju, Sneed, Rosie, Salamanca, Clara, Li, Xin, Xu, Jingwen, Kumar, Deepak, Rosen, Eliot M., Saha, Tapas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3365892/
https://www.ncbi.nlm.nih.gov/pubmed/22685544
http://dx.doi.org/10.1371/journal.pone.0037697