CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments

Three distinct promoters control the master regulator of MHC class II expression, CIITA, in a cell type specific manner. Promoter I (pI) CIITA, expressed primarily by dendritic cells and macrophages, expresses a unique isoform that contains a caspase recruitment domain. The activity and function of...

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Detalles Bibliográficos
Autores principales: Zinzow-Kramer, Wendy M., Long, Alyssa B., Youngblood, Benjamin A., Rosenthal, Kristen M., Butler, Royce, Mohammed, Ata-Ur-Rasheed, Skountzou, Ioanna, Ahmed, Rafi, Evavold, Brian D., Boss, Jeremy M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366023/
https://www.ncbi.nlm.nih.gov/pubmed/22218223
http://dx.doi.org/10.1038/gene.2011.86

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366023/
https://www.ncbi.nlm.nih.gov/pubmed/22218223
http://dx.doi.org/10.1038/gene.2011.86

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