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CIITA promoter I CARD-deficient mice express functional MHC class II genes in myeloid and lymphoid compartments
Three distinct promoters control the master regulator of MHC class II expression, CIITA, in a cell type specific manner. Promoter I (pI) CIITA, expressed primarily by dendritic cells and macrophages, expresses a unique isoform that contains a caspase recruitment domain. The activity and function of...
Autores principales: | Zinzow-Kramer, Wendy M., Long, Alyssa B., Youngblood, Benjamin A., Rosenthal, Kristen M., Butler, Royce, Mohammed, Ata-Ur-Rasheed, Skountzou, Ioanna, Ahmed, Rafi, Evavold, Brian D., Boss, Jeremy M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366023/ https://www.ncbi.nlm.nih.gov/pubmed/22218223 http://dx.doi.org/10.1038/gene.2011.86 |
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