The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55

BACKGROUND AND PURPOSE: Many GPCRs, including the CB(1) cannabinoid receptor, are down-regulated following prolonged agonist exposure by interacting with the GPCR-associated sorting protein-1 (GASP-1). The CB(1) receptor antagonist rimonabant has also recently been described to be an agonist at GPR5...

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Detalles Bibliográficos
Autores principales: Kargl, J, Balenga, NA, Platzer, W, Martini, L, Whistler, JL, Waldhoer, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2012
Materias:
Themed Section: Research Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366063/
https://www.ncbi.nlm.nih.gov/pubmed/21718301
http://dx.doi.org/10.1111/j.1476-5381.2011.01562.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366063/
https://www.ncbi.nlm.nih.gov/pubmed/21718301
http://dx.doi.org/10.1111/j.1476-5381.2011.01562.x

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