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The GPCR-associated sorting protein 1 regulates ligand-induced down-regulation of GPR55
BACKGROUND AND PURPOSE: Many GPCRs, including the CB(1) cannabinoid receptor, are down-regulated following prolonged agonist exposure by interacting with the GPCR-associated sorting protein-1 (GASP-1). The CB(1) receptor antagonist rimonabant has also recently been described to be an agonist at GPR5...
Autores principales: | Kargl, J, Balenga, NA, Platzer, W, Martini, L, Whistler, JL, Waldhoer, M |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366063/ https://www.ncbi.nlm.nih.gov/pubmed/21718301 http://dx.doi.org/10.1111/j.1476-5381.2011.01562.x |
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