Menin liver-specific hemizygous mice challenged with high fat diet show increased weight gain and markers of metabolic impairment

OBJECTIVE: The menin tumor suppressor protein is abundantly expressed in the liver, although no function has been identified because of lack of tumor development in multiple endocrine neoplasia type 1 (Men1) null livers. We examine the phenotype of mice lacking one functional allele of Men1 (consist...

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Detalles Bibliográficos
Autores principales: Wuescher, L, Angevine, K, Patel, P R, Mensah-Osman, E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366066/
https://www.ncbi.nlm.nih.gov/pubmed/23168387
http://dx.doi.org/10.1038/nutd.2012.7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366066/
https://www.ncbi.nlm.nih.gov/pubmed/23168387
http://dx.doi.org/10.1038/nutd.2012.7

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