Cargando…
Menin liver-specific hemizygous mice challenged with high fat diet show increased weight gain and markers of metabolic impairment
OBJECTIVE: The menin tumor suppressor protein is abundantly expressed in the liver, although no function has been identified because of lack of tumor development in multiple endocrine neoplasia type 1 (Men1) null livers. We examine the phenotype of mice lacking one functional allele of Men1 (consist...
Autores principales: | Wuescher, L, Angevine, K, Patel, P R, Mensah-Osman, E |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366066/ https://www.ncbi.nlm.nih.gov/pubmed/23168387 http://dx.doi.org/10.1038/nutd.2012.7 |
Ejemplares similares
-
Loss of menin mediated by endothelial cells treated with CoPP is associated with increased maturation of adipocytes
por: Angevine, Kristine, et al.
Publicado: (2013) -
Menin and GIP are inversely regulated by food intake and diet via PI3/AKT signaling in the proximal duodenum
por: Angevine, K R, et al.
Publicado: (2012) -
Menin‐regulated Pbk controls high fat diet‐induced compensatory beta cell proliferation
por: Ma, Jian, et al.
Publicado: (2021) -
Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism
por: Chou, Chih-Wei, et al.
Publicado: (2020) -
The role of menin in bone pathology
por: Gorbacheva, Anna, et al.
Publicado: (2022)