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In vitro differentiation of mouse embryonic stem cells into inner ear hair cell-like cells using stromal cell conditioned medium

Hearing loss is mainly caused by loss of sensory hair cells (HCs) in the organ of Corti or cochlea. Although embryonic stem (ES) cells are a promising source for cell therapy, little is known about the efficient generation of HC-like cells from ES cells. In the present study, we developed a single-m...

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Detalles Bibliográficos
Autores principales: Ouji, Y, Ishizaka, S, Nakamura-Uchiyama, F, Yoshikawa, M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366087/
https://www.ncbi.nlm.nih.gov/pubmed/22622133
http://dx.doi.org/10.1038/cddis.2012.56