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Chromosomal Aberrations Associated with Clonal Evolution and Leukemic Transformation in Fanconi Anemia: Clinical and Biological Implications

Fanconi anaemia (FA) is an inherited disease with congenital and developmental abnormalities, bone marrow failure, and extreme risk of leukemic transformation. Bone marrow surveillance is an important part of the clinical management of FA and often reveals cytogenetic aberrations. Here, we review bo...

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Detalles Bibliográficos
Autores principales: Meyer, Stefan, Neitzel, Heidemarie, Tönnies, Holger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366199/
https://www.ncbi.nlm.nih.gov/pubmed/22675616
http://dx.doi.org/10.1155/2012/349837