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Aggregated proteins in schizophrenia and other chronic mental diseases: DISC1opathies
Chronic mental diseases (CMD) like the schizophrenias are progressive diseases of heterogenous but poorly understood biological origin. An imbalance in proteostasis is a hallmark of dysfunctional neurons, leading to impaired clearance and abnormal deposition of protein aggregates. Thus, it can be hy...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Landes Bioscience
2012
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366354/ https://www.ncbi.nlm.nih.gov/pubmed/22421208 http://dx.doi.org/10.4161/pri.18989 |