Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

Myocardial dysfunction and coronary macro/microvascular alterations are the hallmarks of diabetic cardiomyopathy and are ascribed to increased oxidative stress and altered nitric oxide synthase (NOS) activity. We hypothesize that pre-treatment by cobalt-protoporphyrin IX (CoPP) ameliorates both myoc...

Descripción completa

Detalles Bibliográficos
Autores principales: Cao, Jian, Vecoli, Cecilia, Neglia, Danilo, Tavazzi, Barbara, Lazzarino, Giuseppe, Novelli, Michela, Masiello, Pellegrino, Wang, Yu-tang, Puri, Nitin, Paolocci, Nazareno, L’Abbate, Antonio, Abraham, Nader G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Research Foundation 2012
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366474/
https://www.ncbi.nlm.nih.gov/pubmed/22675305
http://dx.doi.org/10.3389/fphys.2012.00160

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366474/
https://www.ncbi.nlm.nih.gov/pubmed/22675305
http://dx.doi.org/10.3389/fphys.2012.00160

Ejemplares similares