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Cobalt-Protoporphyrin Improves Heart Function by Blunting Oxidative Stress and Restoring NO Synthase Equilibrium in an Animal Model of Experimental Diabetes

Myocardial dysfunction and coronary macro/microvascular alterations are the hallmarks of diabetic cardiomyopathy and are ascribed to increased oxidative stress and altered nitric oxide synthase (NOS) activity. We hypothesize that pre-treatment by cobalt-protoporphyrin IX (CoPP) ameliorates both myoc...

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Detalles Bibliográficos
Autores principales:	Cao, Jian, Vecoli, Cecilia, Neglia, Danilo, Tavazzi, Barbara, Lazzarino, Giuseppe, Novelli, Michela, Masiello, Pellegrino, Wang, Yu-tang, Puri, Nitin, Paolocci, Nazareno, L’Abbate, Antonio, Abraham, Nader G.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Research Foundation 2012
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366474/ https://www.ncbi.nlm.nih.gov/pubmed/22675305 http://dx.doi.org/10.3389/fphys.2012.00160

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