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Inhibition of Hepatitis C Virus Replication and Viral Helicase by Ethyl Acetate Extract of the Marine Feather Star Alloeocomatella polycladia

Hepatitis C virus (HCV) is a causative agent of acute and chronic hepatitis, leading to the development of hepatic cirrhosis and hepatocellular carcinoma. We prepared extracts from 61 marine organisms and screened them by an in vitro fluorescence assay targeting the viral helicase (NS3), which plays...

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Detalles Bibliográficos
Autores principales: Yamashita, Atsuya, Salam, Kazi Abdus, Furuta, Atsushi, Matsuda, Yasuyoshi, Fujita, Osamu, Tani, Hidenori, Fujita, Yoshihisa, Fujimoto, Yuusuke, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Maekawa, Shinya, Enomoto, Nobuyuki, Nakakoshi, Masamichi, Tsubuki, Masayoshi, Sekiguchi, Yuji, Tsuneda, Satoshi, Akimitsu, Nobuyoshi, Noda, Naohiro, Tanaka, Junichi, Moriishi, Kohji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366673/
https://www.ncbi.nlm.nih.gov/pubmed/22690141
http://dx.doi.org/10.3390/md10040744