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Inhibition of Hepatitis C Virus Replication and Viral Helicase by Ethyl Acetate Extract of the Marine Feather Star Alloeocomatella polycladia
Hepatitis C virus (HCV) is a causative agent of acute and chronic hepatitis, leading to the development of hepatic cirrhosis and hepatocellular carcinoma. We prepared extracts from 61 marine organisms and screened them by an in vitro fluorescence assay targeting the viral helicase (NS3), which plays...
Autores principales: | Yamashita, Atsuya, Salam, Kazi Abdus, Furuta, Atsushi, Matsuda, Yasuyoshi, Fujita, Osamu, Tani, Hidenori, Fujita, Yoshihisa, Fujimoto, Yuusuke, Ikeda, Masanori, Kato, Nobuyuki, Sakamoto, Naoya, Maekawa, Shinya, Enomoto, Nobuyuki, Nakakoshi, Masamichi, Tsubuki, Masayoshi, Sekiguchi, Yuji, Tsuneda, Satoshi, Akimitsu, Nobuyoshi, Noda, Naohiro, Tanaka, Junichi, Moriishi, Kohji |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366673/ https://www.ncbi.nlm.nih.gov/pubmed/22690141 http://dx.doi.org/10.3390/md10040744 |
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