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Monoclonal antibodies targeting the synthetic peptide corresponding to the polybasic cleavage site on H5N1 influenza hemagglutinin

BACKGROUND: Avian influenza H5N1 virus is highly pathogenic partially because its H5 hemagglutinin contains a polybasic cleavage site that can be processed by proteases in multiple organs. METHODS: Monoclonal antibodies (mAb) specific to the synthetic peptide of hemagglutinin polybasic cleavage site...

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Detalles Bibliográficos
Autores principales: Tsai, Henry J, Chi, Li-Ann, Yu, Alice L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366877/
https://www.ncbi.nlm.nih.gov/pubmed/22471562
http://dx.doi.org/10.1186/1423-0127-19-37