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A new analysis approach of epidermal growth factor receptor pathway activation patterns provides insights into cetuximab resistance mechanisms in head and neck cancer

The pathways downstream of the epidermal growth factor receptor (EGFR) have often been implicated to play crucial roles in the development and progression of various cancer types. Different authors have proposed models in cell lines in which they study the modes of pathway activities after perturbat...

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Detalles Bibliográficos
Autores principales: von der Heyde, Silvia, Beissbarth, Tim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366885/
https://www.ncbi.nlm.nih.gov/pubmed/22548923
http://dx.doi.org/10.1186/1741-7015-10-43