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Phenotypic and Transcriptomic Response of Auxotrophic Mycobacterium avium Subsp. paratuberculosis leuD Mutant under Environmental Stress

Mycobacterium avium subsp. paratuberculosis (MAP) is the causative agent of severe gastroenteritis in cattle. To gain a better understanding of MAP virulence, we investigated the role of leuD gene in MAP metabolism and stress response. For this, we have constructed an auxotrophic strain of MAP by de...

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Detalles Bibliográficos
Autores principales: Chen, Jenn-Wei, Scaria, Joy, Chang, Yung-Fu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366959/
https://www.ncbi.nlm.nih.gov/pubmed/22675497
http://dx.doi.org/10.1371/journal.pone.0037884