The Oncoprotein BCL11A Binds to Orphan Nuclear Receptor TLX and Potentiates its Transrepressive Function

Nuclear orphan receptor TLX (NR2E1) functions primarily as a transcriptional repressor and its pivotal role in brain development, glioblastoma, mental retardation and retinopathologies make it an attractive drug target. TLX is expressed in the neural stem cells (NSCs) of the subventricular zone and...

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Detalles Bibliográficos
Autores principales: Estruch, Sara B., Buzón, Víctor, Carbó, Laia R., Schorova, Lenka, Lüders, Jens, Estébanez-Perpiñá, Eva
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366998/
https://www.ncbi.nlm.nih.gov/pubmed/22675500
http://dx.doi.org/10.1371/journal.pone.0037963

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366998/
https://www.ncbi.nlm.nih.gov/pubmed/22675500
http://dx.doi.org/10.1371/journal.pone.0037963

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