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Knockdown of the Fat Mass and Obesity Gene Disrupts Cellular Energy Balance in a Cell-Type Specific Manner

Recent studies suggest that FTO variants strongly correlate with obesity and mainly influence energy intake with little effect on the basal metabolic rate. We suggest that FTO influences eating behavior by modulating intracellular energy levels and downstream signaling mechanisms which control energ...

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Detalles Bibliográficos
Autores principales: Pitman, Ryan T., Fong, Jason T., Billman, Penny, Puri, Neelu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367022/
https://www.ncbi.nlm.nih.gov/pubmed/22675562
http://dx.doi.org/10.1371/journal.pone.0038444