Cargando…

Knockdown of the Fat Mass and Obesity Gene Disrupts Cellular Energy Balance in a Cell-Type Specific Manner

Recent studies suggest that FTO variants strongly correlate with obesity and mainly influence energy intake with little effect on the basal metabolic rate. We suggest that FTO influences eating behavior by modulating intracellular energy levels and downstream signaling mechanisms which control energ...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pitman, Ryan T., Fong, Jason T., Billman, Penny, Puri, Neelu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367022/ https://www.ncbi.nlm.nih.gov/pubmed/22675562 http://dx.doi.org/10.1371/journal.pone.0038444

Ejemplares similares

Mechanism of DNA damage responses induced by exposure to an oligonucleotide homologous to the telomere overhang in melanoma
por: Pitman, Ryan T, et al.
Publicado: (2013)

New fat free mass - fat mass model for use in physiological energy balance equations
por: Thomas, Diana, et al.
Publicado: (2010)

Fat mass and obesity-associated factor (FTO)-mediated N6-methyladenosine regulates spermatogenesis in an age-dependent manner
por: Wu, Yifei, et al.
Publicado: (2023)

High-fat diet disrupts metabolism in two generations of rats in a parent-of-origin specific manner
por: Chambers, T. J. G., et al.
Publicado: (2016)

FTO knockdown in rat ventromedial hypothalamus does not affect energy balance
por: van Gestel, Margriet A., et al.
Publicado: (2014)

The LF/HF ratio does not accurately measure cardiac sympatho-vagal balance
por: Billman, George E.
Publicado: (2013)

Alternative Signaling Pathways as Potential Therapeutic Targets for Overcoming EGFR and c-Met Inhibitor Resistance in Non-Small Cell Lung Cancer
por: Fong, Jason T., et al.
Publicado: (2013)

Complex Relationship between Obesity and the Fat Mass and Obesity Locus
por: Yang, Qingyun, et al.
Publicado: (2017)

Macrophage Depletion Disrupts Immune Balance and Energy Homeostasis
por: Lee, Bonggi, et al.
Publicado: (2014)

Hypothalamic Inflammation and Energy Balance Disruptions: Spotlight on Chemokines
por: Le Thuc, Ophélia, et al.
Publicado: (2017)

HAND1 knockdown disrupts trophoblast global gene expression
por: Fresch, Robert, et al.
Publicado: (2023)

A fat mass and obesity-associated gene polymorphism influences fat mass in exercise-trained individuals
por: Antonio, Jose, et al.
Publicado: (2018)

Personalized Diet in Obesity: A Quasi-Experimental Study on Fat Mass and Fat-Free Mass Changes
por: García-Galbis, Manuel Reig, et al.
Publicado: (2021)

Fat mass to fat-free mass ratio and the risk of non-alcoholic fatty liver disease and fibrosis in non-obese and obese individuals
por: Dai, Huajie, et al.
Publicado: (2021)

Is fat mass & obesity-associated (FTO) gene master regulator of obesity ?
por: Mittal, Balraj, et al.
Publicado: (2016)

Genetic Associations of Obesity: The Fat-Mass and Obesity-Associated (FTO) Gene
por: Ehrlich, Adam C, et al.
Publicado: (2016)

Fat free mass and obesity in relation to educational level
por: Seppänen-Nuijten, Elina, et al.
Publicado: (2009)

How to Estimate Fat Mass in Overweight and Obese Subjects
por: Donini, Lorenzo Maria, et al.
Publicado: (2013)

Obesity, Fat Mass and Immune System: Role for Leptin
por: Francisco, Vera, et al.
Publicado: (2018)

Sirt3 in POMC neurons controls energy balance in a sex- and diet-dependent manner
por: Quiñones, Mar, et al.
Publicado: (2021)

Analysis of time-dependent adaptations in whole-body energy balance in obesity induced by high-fat diet in rats
por: So, Mandy, et al.
Publicado: (2011)

Synergism of EGFR and c-Met pathways, cross-talk and inhibition, in non-small cell lung cancer
por: Puri, Neelu, et al.
Publicado: (2008)

Disruption in daily eating-fasting and activity-rest cycles in Indian adolescents attending school
por: Jain Gupta, Neelu, et al.
Publicado: (2020)

Dynamic Energy Balance and Obesity Prevention
por: Yoo, Sunmi
Publicado: (2018)

Knockdown of ttc26 disrupts ciliogenesis of the photoreceptor cells and the pronephros in zebrafish
por: Zhang, Qi, et al.
Publicado: (2012)

Disruption of Drosophila larval muscle structure and function by UNC45 knockdown
por: Karunendiran, Abiramy, et al.
Publicado: (2021)

Circulating Metabolites Associated with Body Fat and Lean Mass in Adults with Overweight/Obesity
por: Papandreou, Christopher, et al.
Publicado: (2021)

hnRNP C1/C2 and Pur-beta proteins mediate induction of senescence by oligonucleotides homologous to the telomere overhang
por: Mulnix, Richard E, et al.
Publicado: (2013)

Energy balance at the organism and cellular level: effects of biguanides
por: Pollak, Michael
Publicado: (2014)

Negative Energy Balance Does Not Alter Fat-Free Mass During the Yukon Arctic Ultra—The Longest and the Coldest Ultramarathon
por: Schalt, Adriane, et al.
Publicado: (2018)

Comparison of obesity and metabolic syndrome prevalence using fat mass index, body mass index and percentage body fat
por: Wong, Joseph C., et al.
Publicado: (2021)

Cortical astrocytes develop in a plastic manner at both clonal and cellular levels
por: Clavreul, Solène, et al.
Publicado: (2019)

Emerging Function of Fat Mass and Obesity-Associated Protein (Fto)
por: Müller, Timo D., et al.
Publicado: (2013)

Knockdown of the Cellular Protein LRPPRC Attenuates HIV-1 Infection
por: Schweitzer, Cameron J., et al.
Publicado: (2012)

KLHL5 knockdown increases cellular sensitivity to anticancer drugs
por: Schleifer, Robert J., et al.
Publicado: (2018)

Knockdown of the TRPM4 channel alters cardiac electrophysiology and hemodynamics in a sex‐ and age‐dependent manner in mice
por: Arullampalam, Prakash, et al.
Publicado: (2023)

Knockdown of mental disorder susceptibility genes disrupts neuronal network physiology in vitro
por: MacLaren, Erik J., et al.
Publicado: (2011)

In vivo knockdown of Piccolino disrupts presynaptic ribbon morphology in mouse photoreceptor synapses
por: Regus-Leidig, Hanna, et al.
Publicado: (2014)

Rs9939609 Variant of the Fat Mass and Obesity-Associated Gene and Trunk Obesity in Adolescents
por: Mangge, Harald, et al.
Publicado: (2011)

The Role of BMI, Body Fat Mass and Visceral Fat in Executive Function in Individuals with Overweight and Obesity
por: Sánchez-SanSegundo, Miriam, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_jqjicjaie5frh1hrfphvng7d8f