Selective inhibitors of cardiac ADPR cyclase as novel anti-arrhythmic compounds

ADP-ribosyl cyclases (ADPRCs) catalyse the conversion of nicotinamide adenine dinucleotide to cyclic adenosine diphosphoribose (cADPR) which is a second messenger involved in Ca(2+) mobilisation from intracellular stores. Via its interaction with the ryanodine receptor Ca(2+) channel in the heart, c...

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Detalles Bibliográficos
Autores principales: Kannt, Aimo, Sicka, Kerstin, Kroll, Katja, Kadereit, Dieter, Gögelein, Heinz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer-Verlag 2012
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367138/
https://www.ncbi.nlm.nih.gov/pubmed/22526470
http://dx.doi.org/10.1007/s00210-012-0750-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367138/
https://www.ncbi.nlm.nih.gov/pubmed/22526470
http://dx.doi.org/10.1007/s00210-012-0750-2

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