Double threading through DNA: NMR structural study of a bis-naphthalene macrocycle bound to a thymine–thymine mismatch

The macrocyclic bis-naphthalene macrocycle (2,7-BisNP), belonging to the cyclobisintercalator family of DNA ligands, recognizes T–T mismatch sites in duplex DNA with high affinity and selectivity, as evidenced by thermal denaturation experiments and NMR titrations. The binding of this macrocycle to...

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Detalles Bibliográficos
Autores principales: Jourdan, Muriel, Granzhan, Anton, Guillot, Regis, Dumy, Pascal, Teulade-Fichou, Marie-Paule
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Structural Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367172/
https://www.ncbi.nlm.nih.gov/pubmed/22362757
http://dx.doi.org/10.1093/nar/gks067

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367172/
https://www.ncbi.nlm.nih.gov/pubmed/22362757
http://dx.doi.org/10.1093/nar/gks067

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