Ca(2+) improves organization of single-stranded DNA bases in human Rad51 filament, explaining stimulatory effect on gene recombination

Human RAD51 protein (HsRad51) catalyses the DNA strand exchange reaction for homologous recombination. To clarify the molecular mechanism of the reaction in vitro being more effective in the presence of Ca(2+) than of Mg(2+), we have investigated the effect of these ions on the structure of HsRad51...

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Detalles Bibliográficos
Autores principales: Fornander, Louise H., Frykholm, Karolin, Reymer, Anna, Renodon-Cornière, Axelle, Takahashi, Masayuki, Nordén, Bengt
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Genome Integrity, Repair and Replication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367181/
https://www.ncbi.nlm.nih.gov/pubmed/22362735
http://dx.doi.org/10.1093/nar/gks140

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367181/
https://www.ncbi.nlm.nih.gov/pubmed/22362735
http://dx.doi.org/10.1093/nar/gks140

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