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Ca(2+) improves organization of single-stranded DNA bases in human Rad51 filament, explaining stimulatory effect on gene recombination
Human RAD51 protein (HsRad51) catalyses the DNA strand exchange reaction for homologous recombination. To clarify the molecular mechanism of the reaction in vitro being more effective in the presence of Ca(2+) than of Mg(2+), we have investigated the effect of these ions on the structure of HsRad51...
| Autores principales: | , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Oxford University Press
2012
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367181/ https://www.ncbi.nlm.nih.gov/pubmed/22362735 http://dx.doi.org/10.1093/nar/gks140 |