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Exploiting mid-range DNA patterns for sequence classification: binary abstraction Markov models

Messenger RNA sequences possess specific nucleotide patterns distinguishing them from non-coding genomic sequences. In this study, we explore the utilization of modified Markov models to analyze sequences up to 44 bp, far beyond the 8-bp limit of conventional Markov models, for exon/intron discrimin...

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Detalles Bibliográficos
Autores principales: Shepard, Samuel S., McSweeny, Andrew, Serpen, Gursel, Fedorov, Alexei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367190/
https://www.ncbi.nlm.nih.gov/pubmed/22344692
http://dx.doi.org/10.1093/nar/gks154