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Gemin5 proteolysis reveals a novel motif to identify L protease targets

Translation of picornavirus RNA is governed by the internal ribosome entry site (IRES) element, directing the synthesis of a single polyprotein. Processing of the polyprotein is performed by viral proteases that also recognize as substrates host factors. Among these substrates are translation initia...

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Detalles Bibliográficos
Autores principales: Piñeiro, David, Ramajo, Jorge, Bradrick, Shelton S., Martínez-Salas, Encarnación
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3367203/
https://www.ncbi.nlm.nih.gov/pubmed/22362733
http://dx.doi.org/10.1093/nar/gks172